Semler Scientific boosts BTC holdings with $50M purchase

Semler Scientific has expanded its Bitcoin treasury with a $50 million purchase of 455 BTC, solidifying its position among corporate crypto holders. The Nasdaq-listed medical device maker now holds 4,264 BTC worth approximately $474 million at current prices, according to SEC filings reviewed by CoinTelegraph.

The latest acquisition occurred between May 13-22, 2025, at an average price of $109,801 per Bitcoin including fees. This brings the company’s total Bitcoin investment to $390 million since initiating its digital asset strategy, with holdings now representing nearly 20% of its market capitalization.

Semler funded the purchase through its $500 million at-the-market (ATM) stock offering program, which has already raised $114.8 million through the sale of 3 million shares. Company chairman Eric Semler confirmed the transactions in regulatory filings, stating the moves align with their long-term value creation strategy.

Corporate Bitcoin Strategy Breakdown

Semler’s Bitcoin accumulation strategy features several unique elements that set it apart from other corporate holders:

• Publicly tracked BTC Yield metric (25.8% YTD)
• Dedicated Bitcoin dashboard for investor transparency
• ATM stock sales specifically earmarked for crypto purchases

The company’s BTC Yield calculation compares Bitcoin appreciation against equity dilution from stock sales. This metric reached 25.8% year-to-date through May 22, outperforming traditional investment benchmarks.

Financial Positioning and Market Impact

Despite a $64.7 million net loss in Q1 2025, Semler continues doubling down on Bitcoin:

The aggressive accumulation makes Semler the 12th-largest corporate Bitcoin holder worldwide, surpassing several traditional financial institutions. Market analysts note the purchases occurred near Bitcoin’s all-time high price range, signaling strong conviction in future appreciation.

Institutional Adoption Trends

Semler’s moves reflect growing institutional interest in Bitcoin as a treasury asset, despite recent price volatility. The company joins MicroStrategy and Tesla in using equity markets to fund crypto acquisitions, though with a unique focus on medical technology profits financing digital asset positions.

Market reactions have been mixed – SMLR stock swung 14% following the announcement before settling 3.2% lower. Short interest remains elevated at 18% of float, suggesting ongoing skepticism about the Bitcoin-heavy strategy.

Industry observers will watch Semler’s next moves closely, as the company still has $385 million remaining in its ATM authorization. Continued Bitcoin purchases could push its holdings into the top 10 corporate addresses by year-end.

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The $50 million purchase reinforces Bitcoin’s growing role in corporate treasury management, though critics question the timing amid regulatory uncertainties. As public companies now hold over 1.5% of Bitcoin’s total supply, such institutional moves continue reshaping crypto market dynamics and traditional finance relationships.